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(2023) 9:e19475

By maintaining the balance between histone acetyltransferases and histone deacetylases/lysine deacetylases and preventing hypermethylation, CVD-causing factors such as OS, cell proliferation, and inflammation can be mitigated

Although some of the physical findings are more commonly observed in ALD (parotid enlargement, Dupuytren's contracture, and especially those signs associated with feminization) than in non-ALD, no single physical finding or constellation of findings is 100% specific or sensitive for ALD

Studies have shown that IL-6 and TNF- play important roles in promoting early thrombosis in AVF, and increases in CRP and fibrinogen also lead to AVF failure (70, 71)